A herniated disc is one of the most common causes. Spinal bone overgrowth and spinal narrowing can also put pressure on nerve roots.
B12 deficiency, by contrast, can cause peripheral neuropathy.
Because both conditions can involve tingling, numbness, weakness, and leg discomfort, symptoms can sometimes seem similar.
The correct treatment depends on identifying the actual cause.
Who Is More Likely to Develop B12 Deficiency?
Some people have a greater risk of becoming deficient.
Older adults deserve particular attention because the body’s ability to absorb B12 from food can decline with age.
Other risk factors include digestive disorders that interfere with nutrient absorption, gastrointestinal surgery, pernicious anemia, and diets containing little or no animal-derived food.
Certain medications can matter too.
For example, long-term use of metformin and stomach-acid-reducing medications such as proton pump inhibitors can reduce B12 absorption in some people.
That doesn’t mean these medicines should be stopped.
Instead, someone with risk factors and compatible symptoms can ask their healthcare provider whether B12 testing is appropriate.
Foods Naturally Rich in Vitamin B12
Vitamin B12 naturally occurs primarily in animal-derived foods.
Useful dietary sources include fish, meat, poultry, eggs, milk, and other dairy products. Some breakfast cereals and other foods are also fortified with B12.
People following vegan diets generally need to obtain B12 from fortified foods or an appropriate supplement because plant foods don’t naturally provide meaningful amounts of B12.
However, eating extra B12-rich foods won’t necessarily correct a deficiency caused by poor absorption.
Some people require supplements or medically prescribed B12 treatment.
Should Everyone With Sciatica Take B12?
No.
If your B12 level is already adequate, there’s no good evidence that simply taking extra B12 will correct a compressed nerve root in your spine.
That’s why treating every case of leg pain with vitamin supplements can delay finding the real cause.